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Withdrawal symptoms may be so severe that patients are unable to continue reducing the dose, regardless of the medication’s efficacy. In 2010, the Tapering Project was started to address these problems through the development of tapered doses of medication provided in strip packaging: tapering strips.

The reduction or discontinuation of psychiatric medications such as antidepressants, antipsychotics or anxiolytics can cause physical and psychological withdrawal and rebound symptoms.

Withdrawal symptoms may be so severe that patients are unable to continue reducing the dose

Regardless of the medication’s efficacy. Tapering strips allow patients to regulate the tempo of their dose reduction over time and enable them to taper more gradually, conveniently and safely than is possible using currently available standard medication, thereby preventing withdrawal symptoms.

Sigmund Good luck tapering strip

In a tapering strip, medication is packaged in a roll or strip of small daily pouches

Each pouch is numbered and has the same or slightly lower dose than the package before it. Strips come in series covering 28 days and patients can use one or more strips to regulate the tempo of their dose reduction over time. Dose and day information printed on each pouch allow patients to precisely record and monitor the progress of their reduction.

Tapering strips are developed for medication in cases where doing so improves the medical care available and meets an unmet need.

Professor Jim van Os on recent research on taperingstrips

World tapering Day webinar presentation, november 2022: Jim van Os on recent research on taperingstrips

Looking for more information on tapering strips?

Prof. dr. Jim van Os, Chair Division Neuroscience, Utrecht University Medical Centre. Jim is also Visiting Professor of Psychiatric Epidemiology at the Institute of Psychiatry in London. Jim works at the interface of ‘hard’ brain science, health services research, art and subjective experiences of people with ‘lived experience’ in mental healthcare. 

Jim has been appearing on the Thomson-Reuter Web of Science list of ‘most influential scientific minds of our time’ since 2014. In 2014 he published his book ‘Beyond DSM-5‘, and in 2016 the book ‘Good Mental Health Care’. In 2026 he published 'Wat psychisch lijden is'.

Want to read more?

Blogs by Jim van Os can be read here

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